Journal of Child Neurology

 

Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

http://mc.manuscriptcentral.com/childneurology

Click here for more information

Sign In to gain access to subscriptions and/or personal tools.
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrow Add to My Marked Citations
Google Scholar
Right arrow Articles by Golomb, M. R.
Right arrow Articles by Williams, L. S.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Golomb, M. R.
Right arrow Articles by Williams, L. S.
Social Bookmarking
 Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
Journal of Child Neurology, Vol. 23, No. 3, 279-286 (2008)
DOI: 10.1177/0883073807309246
© 2008 SAGE Publications

Cerebral Palsy After Perinatal Arterial Ischemic Stroke

Meredith R. Golomb, MD, MSc

Division of Pediatric Neurology, Indiana University School of Medicine, mgolomb{at}iupui.edu

Bhuwan P. Garg, MBBS

Division of Pediatric Neurology, Indiana University School of Medicine

Chandan Saha, PhD

Division of Biostatistics Indiana University School of Medicine

Faouzi Azzouz, MSc

Division of Biostatistics Indiana University School of Medicine

Linda S. Williams, MD

Department of Neurology, Indiana University School of Medicine, Roudebush Veterans' Affairs Medical Center Health Services Research and Development Service, Regenstrief Institute Indianapolis, Indiana

The frequency of cerebral palsy, degree of disability, and predictors of disability were assessed in children in a perinatal arterial stroke database. Risk factors were assessed at the univariate level using the Pearson {chi}2 and Fisher exact test and at the multivariate level using logistic regression analysis. Seventy-six of 111 children with perinatal stroke (68%) had cerebral palsy, most commonly hemiplegic (66/76; 87%). Multivariate analysis of the entire cohort showed both delayed presentation (OR,9.96; 95% CI, 3.10-32.02) and male sex (OR, 2.55; 95% CI, 1.03-6.32) were associated with cerebral palsy. In subgroup multivariate analyses: in children with neonatal presentation, bilateral infarcts were associated with triplegia or quadriplegia (OR, 5.33; 95% CI, 1.28-22.27); in children with unilateral middle cerebral artery infarcts, delayed presentation (OR, 10.60; 95% CI, 2.28-72.92) and large-branch infarction (OR, 8.78; 95% CI, 2.18-43.67) were associated with cerebral palsy. These data will aid physicians in planning long-term rehabilitative care for children with perinatal stroke.

Key Words: cerebral palsy • outcomes • perinatal • arterial ischemic stroke


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?