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This version was published on May 1, 2008
Journal of Child Neurology, Vol. 23, No. 5, 589-592 (2008)
DOI: 10.1177/0883073807309790
© 2008 SAGE Publications

Hemorrhagic Shock and Encephalopathy Syndrome: Clinical Course and Neurological Outcome

Roni Gefen, MD

Pediatric Division, Assaf Harofeh Medical Center, ronigef{at}gmail.com

Gideon Eshel, MD

Pediatric Intensive Care Unit, Assaf Harofeh Medical Center

Ibrahim Abu-Kishk, MD

Pediatric Intensive Care Unit, Assaf Harofeh Medical Center

Eli Lahat, MD

Pediatric Neurology Department, Assaf Harofeh Medical Center

Ilan Youngster, MD

Pediatric Division, Assaf Harofeh Medical Center

Ehud Rosenbloom, MD

Pediatric Division, Assaf Harofeh Medical Center

Eran Kozer, MD

Pediatric Emergency Medicine Service (EK), Assaf Harofeh Medical Center, Zerifin, Israel

The syndrome of hemorrhagic shock and encephalopathy is associated with an acute onset of diarrhea, followed by shock, disseminated intravascular coagulopathy, multiorgan failure, and encephalopathy. The etiology of this syndrome is unknown, and despite intensive treatment, the outcome is often fatal or associated with severe neurological sequelae. Two infants aged 6 and 9 months were admitted with this syndrome within a 24-hour time interval. The authors hereby present the clinical course and a prospective evaluation of the neurological outcome. A review of the literature regarding this infrequent syndrome is presented.

Key Words: diarrhea • multiorgan failure • hemorrhagic shock and encephalopathy syndrome


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