Journal of Child Neurology

 

Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

http://mc.manuscriptcentral.com/childneurology

Click here for more information

Sign In to gain access to subscriptions and/or personal tools.
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Google Scholar
Right arrow Articles by Williams, B. J.
Right arrow Articles by Maria, B. L.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Williams, B. J.
Right arrow Articles by Maria, B. L.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
Journal of Child Neurology, Vol. 23, No. 6, 699-702 (2008)
DOI: 10.1177/0883073807313040

Increased Intracranial Pressure in a Case of Pediatric Multiple Sclerosis

Brice J. Williams, BS

Department of Neurosciences, Medical University of South Carolina

Holly J. Skinner, DO

Department of Neurosciences, Medical University of South Carolina

Bernard L. Maria, MD, MBA

Department of Neurosciences, Medical University of South Carolina, mariabl{at}musc.edu, Department of Pediatrics Charles P. Darby Children's Research Institute, Medical University of South Carolina, Charleston

A 15-year-old girl presented to our emergency department with dizziness, anorexia, nausea, and malaise. Clinical examination and magnetic resonance imaging studies showed characteristic features of multiple sclerosis. Surprisingly, a diagnostic lumbar puncture showed significant intracranial hypertension in addition to numerous oligoclonal bands, elevated immunoglobulin G index and immunoglobulin G/albumin ratio in the cerebrospinal fluid. It is proposed that a large burden of active demyelinating disease may cause increased intracranial pressure, thus providing an additional sound rationale for prompt therapeutic administration of intravenous high-dose steroids.

Key Words: pediatric multiple sclerosis • increased intracranial pressure


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?