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Journal of Child Neurology
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Divergent Ependymal Tumor (Ependymoblastoma/Anaplastic Ependymoma) of the Posterior Fossa: An Uncommon Case Observed in a Child

Javier Ortiz, MD

Department of Pathology, Hospital Universitario de Salamanca, Spain, jortiz{at}usal.es

Alvaro Otero, MD

Department of Neurosurgery, Hospital Universitario de Salamanca, Spain

Oscar Bengoechea, MD

Department of Pathology, Hospital Universitario de Salamanca, Spain.

Jesús Gonçalves, MD

Department of Neurosurgery, Hospital Universitario de Salamanca, Spain

Pablo Sousa, MD

Department of Neurosurgery, Hospital Universitario de Salamanca, Spain

Javier Figols, MD

Department of Pathology, Hospital Universitario Marqués de Valdecilla, Santander, Spain

Agustín Bullón, MD

Department of Pathology, Hospital Universitario de Salamanca, Spain.

We report a divergent ependymal tumor of the posterior fossa (ependymoblastoma/anaplastic ependymoma) observed in an 8-year-old boy. The tumor showed the histological pattern typical of an ependymoblastoma (tubular-papillary fetaloid architecture with stratification of the tumor cells) next to areas in which findings typical of an anaplastic ependymoma were detected. The immunohistochemical study confirmed our diagnostic suspicion, allowing us to establish a differential diagnosis with other entities such as medulloblastoma, medulloepithelioma, atypical rhabdoid/teratoid tumor, or metastases.

Key Words: ependymoblastoma • anaplastic ependymoma • divergent ependymal tumor

Journal of Child Neurology, Vol. 23, No. 9, 1058-1061 (2008)
DOI: 10.1177/0883073808314160
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