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Journal of Child Neurology
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Posterior Cerebral Artery Occlusion After Mycoplasma pnuemoniae Infection Associated With Genetic Defect of MTHFR C677T

Ju Seok Ryu, MD

Department of Physical Medicine and Rehabilitation, University of Ulsan College of Medicine, Seoul, Korea

Ha Jung Kim, MD

Department of Physical Medicine and Rehabilitation, University of Ulsan College of Medicine, Seoul, Korea

In Young Sung, MD, PhD

Department of Physical Medicine and Rehabilitation, University of Ulsan College of Medicine, Seoul, Korea, iysung{at}amc.seoul.kr

Tae Sung Ko, MD, PhD

Department of Pediatrics Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

Cerebral artery occlusion in childhood, particularly in the posterior circulation, is a rare neurological complication of Mycoplasma pneumoniae infection. A genetic defect in the methylenetetrahydrofolate reductase gene could result in hyperhomocysteinemia and increased risk of stroke. We report a patient with posterior cerebral artery occlusion after Mycoplasma pneumoniae infection associated with a homozygous, methylenetetrahydrofolate reductase gene mutant type.

Key Words: stroke • Mycoplasma pneumoniae • hyperhomocysteinemia • methylenetetrahydrofolate reductase

Journal of Child Neurology, Vol. 24, No. 7, 891-894 (2009)
DOI: 10.1177/0883073808331081
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