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Journal of Child Neurology
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Autonomic Dysfunction and Adrenocortical Unresponsiveness to ACTH

George Makari, MD

Department of Neurology, Medical College of Georgia

William H. Hoffman, MD

Department of Pediatrics, Medical College of Georgia

James E. Carroll, MD

Department of Pediatrics, Medical College of Georgia, Departments of Cell and Molecular Biology, Medical College of Georgia

Diane R. Savage, MD

Department of Pediatrics, Medical College of Georgia

Theodora Van der Zalm, MD

Department of Radiology Medical College of Georgia, Augusta, GA

A child is reported with adrenocortical unresponsiveness to ACTH and autonomic dysfunction. The latter consisted of cold extremities, progressive loss of tear production, the development of achalasia of the esophagus, pupillary dysfunction, and an abnormal histamine skin test. These findings suggest progressive parasympathetic denervation as a cause for the adrenocortical abnormality. (J Child Neurol 1988;3:174-176).

Journal of Child Neurology, Vol. 3, No. 3, 174-176 (1988)
DOI: 10.1177/088307388800300304
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