This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Afifi, A. K. Articles by Wells, K. K. Search for Related Content PubMed PubMed Citation Articles by Afifi, A. K. Articles by Wells, K. K. Social Bookmarking                         What's this?

Seizure-Induced Miosis and Ptosis: Association With Temporal Lobe Magnetic Resonance Imaging Abnormalities

Departments of Pediatrics, Neurology, Ophthalmology, and Anatomy, College of Medicine, University of Iowa, Iowa City, IA

James J. Corbett, MD

Departments of Pediatrics, Neurology, Ophthalmology, and Anatomy, College of Medicine, University of Iowa, Iowa City, IA

H. Stanley Thompson, MD

Departments of Pediatrics, Neurology, Ophthalmology, and Anatomy, College of Medicine, University of Iowa, Iowa City, IA

Kristen K. Wells, MD

Departments of Pediatrics, Neurology, Ophthalmology, and Anatomy, College of Medicine, University of Iowa, Iowa City, IA

Two patients with seizure-associated miosis and ptosis are described. In both there are magnetic resonance imaging abnormalities of the temporal lobe. In one patient, increased magnetic resonance imaging signal intensity is present in the temporal lobe contralateral to ptosis and miosis. In the other, there is temporal lobe asymmetry with the smaller temporal lobe ipsilateral to the miotic pupil and ptotic lid. The relevant human and experimental literature related to cortical control of pupil size and lid movement is reviewed. Based on the available literature and the findings in these two patients, it is proposed that the increased signal intensity in the temporal lobe of one patient represents an irritative stimulus causing contralateral miosis and ptosis, whereas the temporal lobe hypoplasia in the second patient permitted impulses from the contralateral normal temporal lobe to predominate, resulting in miosis and ptosis homolateral to the hypoplastic temporal lobe. (J Child Neurol 1990;5:142-146).

Journal of Child Neurology, Vol. 5, No. 2, 142-146 (1990)
DOI: 10.1177/088307389000500215


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?