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Reduced Regional Cerebral Metabolic Rate for Glucose at the Terminal Stage in a Case of Late Infantile Neuronal Ceroid Lipofuscinosis

Department of Pediatrics, Tohoku University School of Medicine, Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan

Kazuie Iinuma, MD

Department of Pediatrics, Tohoku University School of Medicine, Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan

Akira Kojima, MD

Department of Pediatrics, Tohoku University School of Medicine, Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan

Kazuhiko Yanai, MD

Department of Pediatrics, Tohoku University School of Medicine, Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan

Kazuhiro Haginoya, MD

Department of Pediatrics, Tohoku University School of Medicine, Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan

Keiya Tada, MD

Department of Pediatrics, Tohoku University School of Medicine, Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan

Tatsuo Ido, PhD

Division of Radiopharmaceutical Chemistry, Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan

Masatoshi Ito, MD

Division of Nuclear Medicine Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan

Regional cerebral metabolic rate for glucose was determined for six different areas of the gray matter in an 8-year-old girl with late infantile neuronal ceroid lipofuscinosis. In all regions, the rates were almost half of the control values. The regional cerebral metabolic rate for glucose was relatively preserved in the striatal region and severely reduced in the frontal cortex. (J Child Neurol 1990;5:98-100).

Journal of Child Neurology, Vol. 5, No. 2, 98-100 (1990)
DOI: 10.1177/088307389000500205


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