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Journal of Child Neurology
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Cerebral Infarcts and Seizures in the Neonate

Kosaburou Aso, MD

Developmental Neurophysiology Laboratory, Magee-Womens Hospital

Mark S. Scher, MD

Developmental Neurophysiology Laboratory, Magee-Womens Hospital

Mamdouha Abdab Barmada, MD

Department of Pathology, Children's Hospital of Pittsburgh (Dr Barmada), Pittsburgh, PA

A retrospective analysis was performed on 54 infants who suffered perinatal hypoxic-ischemic insults and came to autopsy, in an attempt to assess the association of cerebral infarcts with seizures. Fifty infants had several types of cerebrovascular Iesions, including intraventricular hemorrhage (32 cases), periventricular leukomalacia (24), ischemic neuronal necrosis (18), pontosubicular necrosis (12), cerebral infarct (9), and cerebellar hemorrhage (7). Of these infants, nine had electroencephalographic seizures. Among a variety of cerebrovascular lesions, cerebral infarcts represented the single lesion most highly correlated with seizures. The incidence of seizures in infants with cerebral infarcts (44%) was significantly higher than with other types of vascular lesions. (J Child Neitrol 1990;5:224-228).

Journal of Child Neurology, Vol. 5, No. 3, 224-228 (1990)
DOI: 10.1177/088307389000500315
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