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Journal of Child Neurology
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Topical Review Article: Pharmacologic Management of Neonatal Cerebral Ischemia and Hemorrhage: Old and New Directions

Van S. Miller, PhD, MD

Division of Pediatric Neurology, University of Texas Southwestern Medical School, Dallas, TX

New developments in pharmacologic management of cerebral ischemia and hemorrhage are reviewed. A number of agents with diverse modes of action have now been shown to be neuroprotective in adult and neonatal animal models when administered either before or after a hypoxic-ischemic insult. As experience improves with these agents in hypoxic-ischemic injury and periventricular-intraventricular hemorrhage in human neonates, there is reason to be optimistic that effective neuroprotective strategies will soon be clinically available. (J Child Neurol 1993;8:7-18) .

Journal of Child Neurology, Vol. 8, No. 1, 7-18 (1993)
DOI: 10.1177/088307389300800102


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I. J. Butler
Cerebrovascular Disorders of Childhood
J Child Neurol, July 1, 1993; 8(3): 197 - 200.
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