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Paroxysmal Kinesigenic Dystonia After Methylphenidate Administration

Department of Pediatrics (Neurology), The University of Texas Health Science Center at San Antonio, San Antonio, TX

Stephen G. Ryan, MD

Department of Pediatrics (Neurology), The University of Texas Health Science Center at San Antonio, San Antonio, TX

We report a patient who developed paroxysmal kinesigenic dystonia shortly after initiation of therapy with methylphenidate for presumed attention deficit-hyperactivity disorder. Attacks persisted long after methylphenidate was discontinued and responded completely to treatment with carbamazepine. Though it is possible that methylphenidate caused this syndrome in our patient, it is more likely that the stimulant triggered the onset of a genetically determined disorder. (J Child Neurol 1994;9:45-46).

Journal of Child Neurology, Vol. 9, No. 1, 45-46 (1994)
DOI: 10.1177/088307389400900110


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