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Disseminated Multifocal Herpes Zoster Leukoencephalitis and Subcortical Hemorrhage in an Immunosuppressed Child

Department of Neurology, Stanford University, Palo Alto, CA

Jin S. Hahn, MD

Department of Neurology, Stanford University, Palo Alto, CA

We describe a rare case of multifocal varicella-zoster leukoencephalitis in an immunosuppressed adolescent boy who developed a herpetiform rash on his groin and subsequently presented with a subacute encephalopathy, aphasia, and hemiparesis. Magnetic resonance imaging scan of the brain revealed multifocal bihemispheric targetlike lesions predominantly in the white matter. A magnetic resonance imaging scan 2 weeks later showed a subcortical hemorrhage in the left insular region. He received long-term high-dose intravenous acyclovir and had significant improvement in his neurologic status. (J Child Neurol 1994;9:56-58).

Journal of Child Neurology, Vol. 9, No. 1, 56-58 (1994)
DOI: 10.1177/088307389400900114


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