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Journal of Child Neurology
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*Vasculitis
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Cardiac and Central Nervous System Vasculitis in a Child With Dermatomyositis

Cita Jimenez, MD

Department of Pediatrics, University of Ottawa School of Medicine, Ottawa, Ontario, Canada

Peter C. Rowe, MD

Department of Pathology University of Ottawa School of Medicine, Ottawa, Ontario, Canada

Daniel Keene, MD

Department of Pathology University of Ottawa School of Medicine, Ottawa, Ontario, Canada

Cerebral vasculitis and clinically important myocardial inflammation are rare in juvenile dermatomyositis. We report a previously healthy 6-year-old girl with dermatomyositis who died after a fulminating clinical deterioration. Postmortem examination of the heart revealed characteristic endothelial tubuloreticular aggregates and evidence of capillary necrosis and secondary thrombosis, associated with extensive hemorrhagic myocardial necrosis. Endothelial necrosis was also evident in the cerebrocortical capillaries. (J Child Neurol 1994;9:297-300).

Journal of Child Neurology, Vol. 9, No. 3, 297-300 (1994)
DOI: 10.1177/088307389400900315
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This article has been cited by other articles:


Home page
 Rheumatology (Oxford)Home page
A. V. Ramanan, S. Sawhney, and K. J. Murray
Central nervous system complications in two cases of juvenile onset dermatomyositis
Rheumatology, November 1, 2001; 40(11): 1293 - 1298.
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