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Journal of Child Neurology
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Article

Cerebral Venous Thrombosis After Immune Thrombocytopenic Purpura and Anti-D Immune Globulin Therapy

Husam R. Kayyali, MD, Ahmed T. Abdelmoity, MD, M. Craig Morriss, MD, and William D. Graf, MD*

* To whom correspondence should be addressed. E-mail: wdgraf{at}cmh.edu.


   Abstract
Cerebral venous thrombosis has multiple etiologies and a wide variety of clinical manifestations. This article reports on a young girl who developed cerebral venous thrombosis after intravenous anti-D immune globulin therapy for immune thrombocytopenic purpura. In this case, venous infarction was manifested by an unusual pattern of restricted diffusion limited to the corpus callosum. The cause of cerebral venous thrombosis in this patient may be related to both immune thrombocytopenia and immunoglobulin therapy.

First published on January 9, 2008, doi:10.1177/0883073807309251

Journal of Child Neurology 2008;23:325.

A more recent version of this article appeared on March 1, 2008


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