This Article Full Text (OnlineFirst PDF) All Versions of this Article: 0883073807309773v1 23/5/486    most recent Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Catroppa, C. Articles by Coleman, L. Search for Related Content PubMed PubMed Citation Articles by Catroppa, C. Articles by Coleman, L. Pubmed/NCBI databases Medline Plus Health Information Learning Disorders MRI Scans Traumatic Brain Injury Social Bookmarking                         What's this?

Using Magnetic Resonance Imaging to Predict New Learning Outcome at 5 Years After Childhood Traumatic Brain Injury

Royal Children’s Hospital, Melborne, Australia

^* To whom correspondence should be addressed. E-mail: cathy.catroppa{at}mcri.edu.au.

	Abstract

Memory and learning entail the recruitment of a number of neural areas, including the medial temporal lobes, temporal association areas, and prefrontal cortices. This study examined the effects of injury severity on long-term memory function in 55 children who sustained traumatic brain injury 5 years earlier and compared this with 17 healthy controls. It also investigated cortical damage and diffuse axonal injury and their association to memory and learning outcomes 5 years after traumatic brain injury. Children were administered memory tests of increasing complexity. Results indicated that injury severity affected aspects of complex memory, with no significant influence on working memory; that focal cortical damage was not predictive of working or complex memory, whereas diffuse axonal injury predicted outcome on complex memory tasks. Findings suggest that the implementation of diffuse axonal injury as an index of injury may assist in predicting memory outcome after childhood traumatic brain injury.

First published on January 9, 2008, doi:10.1177/0883073807309773

Journal of Child Neurology 2008;23:486.

A more recent version of this article appeared on May 1, 2008


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?