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Journal of Child Neurology
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0883073808315416v1
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Article

Cryptogenic Stroke in a Boy With Atrial Septal Defect and Hyperhomocysteinemia

Giuseppe Indolfi, MD*, Elisa Bartolini, MD, Sandra Trapani, MD, PhD, Chiara Azzari, MD, PhD, and Massimo Resti, MD

the Department of Pediatrics, University of Florence, Anna Meyer Children’s Hospital, Florence, Italy

* To whom correspondence should be addressed. E-mail: g.indolfi{at}meyer.it.


  Abstract
In children, clinical recognition of stroke and determination of its exact etiology are extremely difficult. The authors described a case of cryptogenic stroke in a 14-year-old-boy with asymptomatic atrial septal defect and hypercoagulable state. Paradoxical embolism was hypothesized as the responsible etiopathological mechanism. It is crucial to increase clinician awareness of stroke in children.

First published on May 12, 2008, doi:10.1177/0883073808315416

Journal of Child Neurology 2008;23:1070.

A more recent version of this article appeared on September 1, 2008

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