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Journal of Child Neurology
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0883073808315419v1
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Article

A Case of Pediatric Tumefactive Demyelinating Lesion Misdiagnosed and Treated as Glioblastoma

Daria Riva, MD1, Bianca Pollo, MD2, Luisa Chiapparini, MD3, Maria Rosa Balestrini, MD1, Maura Massimino, MD4, and Nicoletta Milani, MD5*

1 Department of Developmental Neurology, Istituto Nazionale Neurologico "C. Besta," Milano, Italy
2 Department of Neuropathology, Istituto Nazionale Neurologico "C. Besta," Milano, Italy
3 Department of Neuroradiology, Istituto Nazionale Neurologico "C. Besta," Milano, Italy
4 Pediatric Oncology, Istituto Nazionale Tumori, Milano, Italy
5 Department of Child Neurology, Istituto Nazionale Neurologico "C. Besta," Milano, Italy

* To whom correspondence should be addressed. E-mail: nmilani{at}istituto-besta.it.


  Abstract
Because of their clinical and neuroradiological features, tumefactive demyelinating lesions, or giant plaques, are easily mistaken for tumors, with a consequent risk of gross errors in the choice of treatment. This article reports a 10-year-old girl who underwent surgery for a left parietal lesion misinterpreted as a glioblastoma which subsequently proved to be a case of giant plaque.

First published on March 14, 2008, doi:10.1177/0883073808315419

Journal of Child Neurology 2008;23:944.

A more recent version of this article appeared on August 1, 2008

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