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Journal of Child Neurology
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0883073808324769v1
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*CYCLOPHOSPHAMIDE
*METHYLPREDNISOLONE
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*Multiple Sclerosis
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Article

Acute Tumefactive Demyelinating Lesions in a Pediatric Patient With Known Diagnosis of Multiple Sclerosis: Review of the Literature and Treatment Proposal

Jahannaz Dastgir, DO and Francis J. DiMario Jr, MD*

Dept of Pediatrics, Div of Child Neurology, Connecticut Children’s Medical Center, Hartford, and the Univ of Connecticut School of Medicine, Farmington, CT

* To whom correspondence should be addressed. E-mail: fdimari{at}ccmckids.org.


   Abstract

Tumefactive demyelinating lesions are a known but uncommon complication of multiple sclerosis, a disease rarely reported in children. This is the case of a 16-year-old African American patient with multiple sclerosis, who developed 2 tumefactive demyelinating lesions. Review of the literature and our own experience helped formulate an algorithm for therapeutic options during an acute attack.

First published on February 2, 2009, doi:10.1177/0883073808324769

Journal of Child Neurology 2009;24:431.

A more recent version of this article appeared on April 1, 2009


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