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Journal of Child Neurology
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Cerebral Venous Thrombosis After Immune Thrombocytopenic Purpura and Anti-D Immune Globulin Therapy

Husam R. Kayyali, MD

Department of Pediatrics, Section of Neurology, University of Missouri Kansas city

Ahmed T. Abdelmoity, MD

Department of Pediatrics, Section of Neurology, University of Missouri Kansas city

M. Craig Morriss, MD

Department of Radiology (MCM), Children's Mercy Hospital and Clinics, University of Missouri Kansas City

William D. Graf, MD

Department of Pediatrics, Section of Neurology, University of Missouri Kansas city, wdgraf{at}cmh.edu

Cerebral venous thrombosis has multiple etiologies and a wide variety of clinical manifestations. This article reports on a young girl who developed cerebral venous thrombosis after intravenous anti-D immune globulin therapy for immune thrombocytopenic purpura. In this case, venous infarction was manifested by an unusual pattern of restricted diffusion limited to the corpus callosum. The cause of cerebral venous thrombosis in this patient may be related to both immune thrombocytopenia and immunoglobulin therapy.

Key Words: cerebral venous thrombosis • immune thrombocytopenic purpura • stroke

This version was published on March 1, 2008

Journal of Child Neurology, Vol. 23, No. 3, 325-330 (2008)
DOI: 10.1177/0883073807309251
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