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Journal of Child Neurology
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A Case of Pediatric Tumefactive Demyelinating Lesion Misdiagnosed and Treated as Glioblastoma

Daria Riva, MD

Department of Developmental Neurology, Istituto Nazionale Neurologico "C. Besta,"

Luisa Chiapparini, MD

Department of Neuroradiology, Istituto Nazionale Neurologico "C. Besta,"

Bianca Pollo, MD

Department of Neuropathology, Istituto Nazionale Neurologico "C. Besta,"

Maria Rosa Balestrini, MD

Department of Developmental Neurology, Istituto Nazionale Neurologico "C. Besta,"

Maura Massimino, MD

Pediatric Oncology, Istituto Nazionale Tumori, Milano, Italy

Nicoletta Milani, MD

Department of Child Neurology, Istituto Nazionale Neurologico "C. Besta," Milano, Italy, nmilani{at}istituto-besta.it

Because of their clinical and neuroradiological features, tumefactive demyelinating lesions, or giant plaques, are easily mistaken for tumors, with a consequent risk of gross errors in the choice of treatment. This article reports a 10-year-old girl who underwent surgery for a left parietal lesion misinterpreted as a glioblastoma which subsequently proved to be a case of giant plaque.

Key Words: tumefactive demyelination • glioblastoma

This version was published on August 1, 2008

Journal of Child Neurology, Vol. 23, No. 8, 944-947 (2008)
DOI: 10.1177/0883073808315419
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